41/68US=58 / Câncer
Pevarello P, Bischoff JR, Mercurio C. Targeting cyclin-dependent kinases with small molecular inhibitors. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 235-44. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

CICLINA DEPENDENTE DE QUINASE; INIBIDOR DE MOLECULA PEQUENA; SELETIVIDADE; DE MULTI-ALVO; ENSAIOS CLINICOS


42/68US=9 / Estatística
Rothman KJ, Greenland S, Lash TL. Study design and conduct: types of epidemiologic studies. In: ___. Modern epidemiology. 3rd ed. Philadelphia: Lippincott Wiilians & Wilkins, 2008. p. 87-99. ISBN 978-0-7817-5564-1.

TIPOS DE ESTUDOS EPIDEMIOLOGICOS; ESTUDOS EXPERIMENTAIS; RANDOMIZACAO; ETICA; EXPERIMENTOS; ENSAIOS CLINICOS; ENSAIOS DE CAMPO; INTERVENCAO COMUNITARIA; ENSAIOS RANDOMIZADOS DE CLUSTER; ESTUDOS NAO EXPERIMENTAIS; ESTUDOS DE COORTE; ESTUDOS CASO-CONTROLE; ESTUDOS PROSPECTIVOS; ESTUDOS RETROSPECTIVOS; ESTUDOS ECOLOGICOS; GERACAO DE HIPOTESES; TRIAGEM DE HIPOTESES


43/68US=7 / Transplante
Scharp DW. Cell therapy for peripheral diseases and reconstructive applications: encapsulated human islet allografts: providing safety with efficacy. In: Halberstadt C, Emerich D, editors. Cellular transplantation: from laboratory to clinic. Amsterdam: Elsevier, 2007. p. 135-53. ISBN 978-0-12-369415-7.

TERAPIA CELULAR; DOENCAS PERIFERICAS; APLICACOES RECONSTRUTIVAS; ILHOTAS HUMANAS; ALOENXERTOS ENCAPSULADOS; TRANSPLANTE DE ILHOTAS CLINICAS; IMUNOSSUPRESSAO; MACROCAPSULAS; MICROCAPSULAS; REVESTIMENTOS ISOLANTES; ENSAIOS CLINICOS; BIOCOMPATIBILIDADE; ESTUDOS EM PEQUENOS ANIMAIS


44/68US=7 / Transplante
Thanos C, Emerich DF. Cell therapy for CNS diseases: neurotrophic cell transplants for degenerative diseases of the eye. In: Halberstadt C, Emerich D, editors. Cellular transplantation: from laboratory to clinic. Amsterdam: Elsevier, 2007. p. 327-43. ISBN 978-0-12-369415-7.

TERAPIA CELULAR; DOENCAS DO SISTEMA NERVOSO CENTRAL; TRANSPLANTES DE CELULAS NEUROTROFICAS; DOENCAS DEGENERATIVAS DO OLHO; OLHO. ANATOMIA; ENCAPSULAMENTO DE CELULAS; IMUNOISOLAMENTO; ENGENHARIA DE ENCAPSULAMENTO DE CELULAS; FATORES NEUROTROFICOS NO OLHO; FATOR NEUROTROFICO CILIAR; FATOR NEUROTROFICO DERIVADO NO CEREBRO; ENSAIOS CLINICOS; RETINITE PIGMENTOSA; DEGENERACAO MACULAR


45/68US=16 / Urologia
Kortenhorst MSQ, Carducci MA, Shabbeer S. Therapeutics: differentiation agents and epigenomic therapies. In: Chung LWK, Isaacs WB, Simons JW. Prostate cancer: biology, genetics, and the new therapeutics. 2ª ed. New Jersey: Humana Press, 2007. p. 411-43. (Contemporary Cancer Research) ISBN 978-1-58829-696-2.

CANCER DE PROSTATA; TERAPEUTICA; AGENTES DE DIFERENCIACAO; TERAPIA EPIGENOMICA; ACETILACAO; MODIFICACAO DA CROMATINA; REMODELAMENTO DA CROMATINA; ENSAIOS CLINICOS; EPIGENETICA; HISTONA ACETIL TRANSFERASE; CODIGO DE HISTONAS; INIBIDOR DE HISTONA-DESACETILASE; METILACAO; INIBIDOR METIL TRANSFERASE


46/68US=16 / Urologia
Rogtko A, Tighiouart M. Therapeutics: novel and efficient translational clinical trial designs in advanced prostate cancer. In: Chung LWK, Isaacs WB, Simons JW. Prostate cancer: biology, genetics, and the new therapeutics. 2ª ed. New Jersey: Humana Press, 2007. p. 487-95. (Contemporary Cancer Research) ISBN 978-1-58829-696-2.

CANCER DE PROSTATA; TERAPEUTICA; PROJETOS DE TRANSLACAO; ENSAIOS CLINICOS; CANCER DE PROSTATA AVANCADO; CONCEPCAO BAYESIANA; ESCALONAMENTO DE DOSE; ESCALADA COM OVERDOSE DE CONTROLE; EWOC; OVERDOSE DE CONTROLE; PROJETO FASE I


47/68US=21 / Neurologia
Kanner AA. Contemporary investigational treatments: convection-enhanced delivery. In: Barnett GH. High-grade gliomas: diagnosis and treatment. New Jersey: Humana Press, 2007. p. 303-14. (Current Clinical Oncology) ISBN 978-1-58829-511-8.

GLIOMA DE ALTO GRAU. TERAPIA; ENTREGA INTENSIFICADA POR CONVECCAO; NEOPLASIA CEREBRAL; TERAPIA ALVO; ENSAIOS CLINICOS


48/68US=21 / Neurologia
Chiocca EA, Lamfers ML. Contemporary investigational treatments: clinical trials of oncolytic viruses for gliomas. In: Barnett GH. High-grade gliomas: diagnosis and treatment. New Jersey: Humana Press, 2007. p. 391-403. (Current Clinical Oncology) ISBN 978-1-58829-511-8.

GLIOMA DE ALTO GRAU. TERAPIA; ENSAIOS CLINICOS; VIRUS ONCOLITICOS; TERAPIA GENICA; TUMOR CEREBRAL; ADENOVIRUS; HERPES SIMPLES


49/68US=35 / Câncer
Estey E. Special challenges: new designs for clinical trials. In: Karp JE. Acute myelogenous leukemia. New Jersey: Humana Press, 2007. p. 399-415. (Contemporary Hematology) ISBN 978-1-58829-621-4.

LEUCEMIA MIELOIDE AGUDA; ENSAIOS CLINICOS; 3 PROJETO 3; MODELOS DE DUAS FASES CONVENCIONAIS; METODOLOGIA BAYESIANA


50/68US=77-J / Câncer
Freitas DS, Freitas HC. Ensaios clínicos. In: Lopes A, Chammas R, Iyeyasu H. Oncologia para a graduação. 3ª ed. São Paulo: Lemar, 2013. p. 209-14. ISBN 8-5866523-7-0.

CANCER; ENSAIOS CLINICOS; PESQUISA CLINICA; PRATICA CLINICA


51/68US=77-J / Câncer
Nishimoto IN, Kowalski LP. Epidemiologia do câncer. In: Lopes A, Chammas R, Iyeyasu H. Oncologia para a graduação. 3ª ed. São Paulo: Lemar, 2013. p. 259-68. ISBN 8-5866523-7-0.

CANCER. EPIDEMIOLOGIA; ESTUDOS EPIDEMIOLOGICOS; ESTUDOS OBSERVACIONAIS; ESTUDOS EXPERIMENTAIS; FONTE DE DADOS; SERIE DE CASOS; ENSAIOS CLINICOS; FATORES DE RISCO


52/68US=8 / Ginecologia
Markman M. Management of ovarian cancer: clinical trials. In: Helm CW. Intraperitoneal cancer therapy. New Jersey: Humana Press, 2007. p. 11-29. ISBN 978-1-58829-878-2.

CANCER DE OVARIO. TRATAMENTO; QUIMIOTERAPIA INTRAPERITONEAL; CANCER DE OVARIO; ENSAIOS CLINICOS


53/68US=95 / Biol/Mol
Fang B, Roth JA. Vectors: adenovector-mediated cancer gene therapy. In: Hunt KK, Vorburger AS, Swisher SG. Gene therapy for cancer. New Jersey: Humana Press, 2007. p. 3-22. (Cancer Drug Discovery and Development) ISBN 978-0-470-19756-1.

CANCER; TERAPIA GENETICA; VETORES; ADENOVETOR MEDIADA; ADENOVIRUS; VETOR ALVO; APOPTOSE; ENSAIOS CLINICOS


54/68US=95 / Biol/Mol
Pin RH, Reinblatt M, Fong Y, Jarnagin WR. Gene therapy approaches: oncolytic herpes simplex for gene therapy in preclinical and clinical trials. In: Hunt KK, Vorburger AS, Swisher SG. Gene therapy for cancer. New Jersey: Humana Press, 2007. p. 213-22. (Cancer Drug Discovery and Development) ISBN 978-0-470-19756-1.

CANCER; TERAPIA GENETICA; VIRUS ONCOLITICOS; HERPES SIMPLEX; ENSAIOS PRE-CLINICOS; ENSAIOS CLINICOS


55/68US=95 / Biol/Mol
Minshi A, Meyn RE. Gene therapy approaches: combination of gene therapy with radiation. In: Hunt KK, Vorburger AS, Swisher SG. Gene therapy for cancer. New Jersey: Humana Press, 2007. p. 243-56. (Cancer Drug Discovery and Development) ISBN 978-0-470-19756-1.

CANCER; TERAPIA GENETICA; RADIACAO IONIZANTE; CARCINOMA; ENSAIOS CLINICOS; RADIOSENSIBILIZACAO; QUIMIOTERAPIA MOLECULAR; TERAPIA ANTIMOLECULAR


56/68US=95 / Biol/Mol
Liu TC, Kirn DH. Clinical applications: problems, side effects, and disappointments in clinical cancer gene therapy. In: Hunt KK, Vorburger AS, Swisher SG. Gene therapy for cancer. New Jersey: Humana Press, 2007. p. 351-85. (Cancer Drug Discovery and Development) ISBN 978-0-470-19756-1.

CANCER; TERAPIA GENETICA; APLICACOES CLINICAS; EFEITOS COLATERAIS; ENSAIOS CLINICOS; VETORES


57/68US=95 / Biol/Mol
Ueno NT, Wolf JK, Gerhenson DM, Hortobagyi GN, Hung MC. Clinical applications: trials and tribulations in developing clinical trials of gene therapy. In: Hunt KK, Vorburger AS, Swisher SG. Gene therapy for cancer. New Jersey: Humana Press, 2007. p. 387-98. (Cancer Drug Discovery and Development) ISBN 978-0-470-19756-1.

CANCER; TERAPIA GENETICA; APLICACOES CLINICAS; ENSAIOS CLINICOS; LIPOSSOMAS CATIONICOS; CANCER DE MAMA; CANCER DE OVARIO; ADENOVIRUS TIPO 5 E1A


58/68US=88 / Biol/Mol
Hellebrekers DMEI, van Engeland M. Clinical trials and approved drugs for epigenetic cancer therapy. In: Tollefsbol T. Cancer epigenetics. Boca Raton: CRC, 2009. p. 415-25. ISBN 978-1-4200-4579-6.

CANCER; EPIGENETICA; ENSAIOS CLINICOS; DROGAS APROVADAS; TERAPIA EPIGENETICA


59/68US=2 / Mama
Simon RM. General topics: guidelines for the design of clinical studies for the development and validation of therapeutically relevant biomarkers and biomarker-based classification systems. In: Gasparini G, Hayes DF. Biomarkers in breast cancer: molecular diagnostics for predicting and monitoring therapeutic effect. New Jersey: Humana Press, 2006. p. 1-15. (Cancer Drug Discovery and Development) ISBN 978-1-58829-227-4.

CANCER DE MAMA; BIOMARCADORES; MICROARRAYS; SISTEMA DE CLASSIFICACAO; ENSAIOS CLINICOS


60/68US=2 / Mama
Daidone MG, Silvestrini R, Amadori D. Tissue predictive biomakers: cell kinetics. In: Gasparini G, Hayes DF. Biomarkers in breast cancer: molecular diagnostics for predicting and monitoring therapeutic effect. New Jersey: Humana Press, 2006. p. 81-109. (Cancer Drug Discovery and Development) ISBN 978-1-58829-227-4.

BIOMARCADORES DE TECIDO PREDITIVOS; CINETICA CELULAR; PADRONIZACAO DO ENSAIO; ENSAIOS CLINICOS; VARIACOES POS-TRATAMENTO


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