521/949US=65 / Biol/Mol
Stoppelli MP, Andersen LM, Votta G, Andreasen PA. Engineered antagonists of uPA and PAI-1. In: Edwards D, Hoyer-Hansen G, Blasi F, Sloane BF. The cancer degradome: proteases and cancer biology. New York: Spriger, 2008. p. 721-58. ISBN 978-0-387-69056-8.

UPA; PAI-1; ATIVACAO DO PLASMINOGENIO; DISSEMINACAO DO CANCER; PROPRIEDADES BIOQUIMICAS; ADESAO CELULAR; MIGRACAO CELULAR; INVASAO CELULAR; PROLIFERACAO CELULAR; SOBREVIVENCIA; APOPTOSE; ATIVIDADE ENZIMATICA

522/949US=67 / Biol/Mol
Knights CD, Pestell RG. The cell cycle: therapeutic targeting of cell regulatory components and effector pathways in cancer. In: Kaufman HL, Wadler S, Antman K. Molecular targeting in oncology. New Jersey: Humana Press, 2008. p. 3-32. (Cancer Drug Discovery and Development) ISBN 978-1-58829-577-4.

CICLO CELULAR; SEGMENTACAO TERAPEUTICA; COMPONENTES CELULARES; VIAS REGULADORAS; CANCER; CICLINA DEPENDENTE DE QUINASE; INIBIDORES CDK; TERAPIA; ACETILACAO; P53; CICLINA D1; EGFR; HDAC; STI-571; FLAVOPIRIDOL; INIBIDOR CDK2

523/949US=67 / Biol/Mol
Gupta A, Kirkwood JM. Melanoma. In: Kaufman HL, Wadler S, Antman K. Molecular targeting in oncology. New Jersey: Humana Press, 2008. p. 343-67. (Cancer Drug Discovery and Development) ISBN 978-1-58829-577-4.

MELANOMA; PATOGENESE MOLECULAR; TERAPIA ALVO; INTERFERON; STAT; ANTISENSE BC12; BRAF; APOPTOSE; CICLO CELULAR

524/949US=67 / Biol/Mol
Borghaei H, Binyamin L, Astsaturov I, Weiner LM. Antibody therapy of cancer. In: Kaufman HL, Wadler S, Antman K. Molecular targeting in oncology. New Jersey: Humana Press, 2008. p. 371-412. (Cancer Drug Discovery and Development) ISBN 978-1-58829-577-4.

CANCER. TERAPIA; ANTICORPOS MONOCLONAIS; TERAPIA DE ANTICORPOS; CITOTOXICIDADE CELULAR DEPENDENTE DE ANTICORPO; CITOTOXICIDADE DEPENDENTE DE COMPLEMENTO; IMUNOCONJUGADOS

525/949US=69 / Câncer
Wheler J, Kurzrock R. Perspectives: bench to bedside and back. In: Kurzrock R, Markman M. Targeted Cancer therapy. 2nd. New Jersey: Humana Press, 2008. p. 1-19. ISBN 978-1-60327-423-4.

TERAPIA DE CANCER DIRECIONADA; MEDICINA TRANSLACIONAL; BIOINFORMATICA; ACIDO TRANS-RETINOICO; GIST; IMATINIB; DASATINIBE; EPIGENETICA; DECITABINA; DETER HIPOTESE CELULAR

526/949US=58 / Câncer
Dijkstra KK, Blanchetot C, Boonstra. Evasion of G1 checkpoints in cancer. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 3-26. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

CONTROLE G1 EM CANCER; CICLO CELULAR; CHECKPOINT G1 CEDO; PONTO DE RESTRICAO; ESTRESSE MITOGENICA HIPER; CHECKPOINT ENERGIA; ROS

527/949US=58 / Câncer
Kaina B, Roos WP, Christmann M. DNA damage response and the balance between cell survival and cell death. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 95-108. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

DANOS NO DNA; SOBREVIVENCIA CELULAR; MORTE CELULAR; CHECKPOINTS; CICLO CELULAR; RESPOSTA A DANOS DO DNA; REPARACAO DO ADN; P53; APOPTOSE; RECEPTORES DE MORTE; FAS; CAIXA ELETRONICO; ATR; DROGAS ANTICANCER

528/949US=58 / Câncer
Pentimalli F, Cito L, Giordano A. Dysfunction of the RB retinoblastoma gene in cancer. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 109-22. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

DISFUNCAO DO GENE; RETINOBLASTOMA RB NO CANCER; RETINOBLASTOMA; FAMILIA RB; SUPRESSORES TUMORAIS; CICLO CELULAR; G1-S DE TRANSICAO; CHECKPOINTS; E2F

529/949US=58 / Câncer
Alao JP. G1 phase cyclins in cancer development and progression. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 123-53. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

FASE G1; CICLINAS EM CANCER; CICLO CELULAR; FASE G1; CICLINA D1; CICLINA E; CANCER; ONCOGENE; UBIQUITINA; PROTEASSOMA 26S; TERAPIA DO CANCER

530/949US=58 / Câncer
Post SM, Quinás-Cardama A, Lozano G. Regulation of p53 activity and associated checkpoint controls. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 171-88. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

P53; MDM2; P19; TUMORIGENESE; CANCER; RAS; CICLO CELULAR; RB; CICLINA; CDK

531/949US=58 / Câncer
Eastman A. The importance of p53 signaling in the response of cells to checkpoint inhibitors. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 189-98. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

DANOS NO DNA; PARADA DO CICLO CELULAR; P53; P21; CICLINA B; CHK1 INIBIDORES; UCN-01; INIBIDORES DA TOPOISOMERASE II; ANALOGOS DE NUCLEOSIDOS

532/949US=58 / Câncer
Siddik ZH. Targeting p21-dependent pathways for cell death in cancer therapy. In: ___. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 199-213. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

DANOS NO DNA; P21; CICLINA DEPENDENTE DE QUINASE; G1 RESPOSTA CHECKPOINT; PARADA DO CICLO CELULAR; TRANSATIVACAO; PARADA DO CICLO GENE

533/949US=58 / Câncer
Le XF, Bast Junior RC. p27Kip1 as a biomark and target for treatment of cancer. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 215-33. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

P27KIP1; CICLO CELULAR; SUPRESSOR DE TUMOR; TERAPIA ALVO; TRASTUZUMAB

534/949US=58 / Câncer
Zhang H, Xiao Z, Sowin T. ChK1 and ChK2 as checkpoint targets. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 245-59. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

CHK1; CHK2; INIBIDORES; PARADA DO CICLO CELULAR; REVOGACAO DA RESPOSTA CHECKPOINT; CHEMOPROTECTION; BIOMARCADORES PREDITIVOS

535/949US=58 / Câncer
Rudolph J. Targeting Cdc25 phosphatases in cancer therapy. In: Siddik ZH. Checkpoint controls and targets in cancer therapy. New Jersey: Humana Press, 2008. p. 261-9. (Cancer Drug Discovery and Development Series) ISBN 978-1-60761-177-6.

CDC25 FOSFATASE; CICLO CELULAR; CANCER; AGENTES ANTI-PROLIFERATIVOS

536/949US=70 / Biol/Mol
Bunz F. Cancer gene pathways. In: ___. Principles of cancer genetics. New York: Springer, 2008. p. 173-226. ISBN 978-1-4020-6783-9.

CANCER; GENE; VIAS; VIAS CELULARES; INTERACAO PROTEINA-PROTEINA; REACOES BIOQUIMICAS; FOSFORILACAO DE PROTEINAS; SINAIS DA SUPERFICIE CELULAR; TIROSINA-QUINASES PROTEICAS; VIA RAS; FOSFORILACAO DE LIPIDIOS; VIA PI3K/AKT; MORFOGENESE; VIA WNT/APC; HOMEOSTASE; ATIVACAO P53; MDM2; APOPTOSE; CICLO CELULAR

537/949US=8 / Dermatologia
Kimyai-Asadi A, Jih MH, Freedberg IM. Epidermal cell kinetics, epidermal differentiation and keratinization. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, editores. Fitzpatrick's dermatology in general medicine. 6th ed. New York: McGraw-Hill, 2008. p. 89-98. ISBN 978-0-07138076-0.

CINETICA CELULAR EPIDERMICA; DIFERENCIACAO EPIDERMICA; QUERATINIZACAO; CINETICA DE CELULAS EPIDERMICAS; CELULAS-TRONCO; CELULAS AMPLIFICADORAS TRANSITORIAS; CELULAS DIFERENCIADAS; EPIDERME; DIFERENCIACAO EPIDERMICA; PROTEINAS DOS FILAMENTOS INTERMEDIOS

538/949US=8 / Dermatologia
Hsieh FH, Brigham CO, Austen KF. The molecular and cellular biology of the mast cell. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, editores. Fitzpatrick's dermatology in general medicine. 6th ed. New York: McGraw-Hill, 2008. p. 330-5. ISBN 978-0-07138076-0.

MASTOCITO; BIOLOGIA MOLECULAR; BIOLOGIA CELULAR; RECEPTORES DE CELULAS MASTRO; LIGANTES; QUIMIOTAXIA

539/949US=8 / Dermatologia
Kraemer KH. Cellular hypersensitivity and DNA repair. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, editores. Fitzpatrick's dermatology in general medicine. 6th ed. New York: McGraw-Hill, 2008. p. 351-8. ISBN 978-0-07138076-0.

HIPERSENSIBILIDADE CELULAR; REPARO DO DNA; HIPERSENSIBILIDADE CELULAR; GENES DE REPARACAO; REPARO POR EXCISAO

540/949US=84 / Biol/Mol
Stuelten CH, Roberts AB, Stetler-Stevenson WG. Basic concepts of TGF-B signaling in normal physiology and cancer pathobiology: functional interactions between MMPs and TGF-B in normal and tumor tissue. In: Jakowlew SB. Transforming growth Factor-beta in cancer therapy: basic and clinical biology. Amsterdam: Elsevier, 2008. p. 275-92. (Cancer Drug Discovery and Development) ISBN 978-1-58829-714-3.

TGF-B; MMP; TUMOR; INTERACAO ESTROMA TUMORAL; SINALIZACAO CELULAR

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