10721/13381US=92 / Biol/Mol
Djavaheri-Mergny M, Botti J, Codogno P. Apoptosis and alternative modes of cell death: autophagy and autophagic cell death. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 93-107. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

AUTOFAGIA; APOPTOSE; MORTE CELULAR; CANCER; MACROAUTOPHAGY; LISOSSOMO; TRANSDUCAO DE SINAL

10722/13381US=92 / Biol/Mol
McConkey DJ, Bondar V. Apoptosis and alternative modes of cell death: regulation and function of detachment-induced death (anoikis) in cancer progression and metastasis. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 109-22. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

INTEGRINA; AKT; CASPASE; BIM; AUTOFAGIA

10723/13381US=92 / Biol/Mol
McConkey DJ, Bondar V. Telomeres and telomerase, senescence, genomic instabilidade, and tumorigenesis: structure and function of the telomere. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 125-44. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

TELOMERASE; ALT; TUMORIGENESIS; INSTABILIDADE GENOMICA; ESTABILIDADE CROMOSSOMO; CANCER; ENVELHECIMENTO

10724/13381US=92 / Biol/Mol
Ramirez RD. Telomeres and telomerase, senescence, genomic instabilidade, and tumorigenesis: overview of senescence. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 145-57. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

SENESCENCIA CELULAR; ENVELHECIMENTO; TELOMEROS; TELOMERASE; ALTERNATIVA PARA ALONGAR OS TELOMEROS; PROBLEMA DE REPLICACAO FINAL

10725/13381US=92 / Biol/Mol
Possemato R, Hahn WC. Telomeres and telomerase, senescence, genomic instabilidade, and tumorigenesis: contributions of telomerase to tumorigenesis. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 159-71. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

TRANSCRIPTASE REVERSA DA TELOMERASE; TELOMERO; TUMORIGENESIS; TRANSFORMACAO; CANCER

10726/13381US=92 / Biol/Mol
Murnane JP. Telomeres and telomerase, senescence, genomic instabilidade, and tumorigenesis: the role of telomeres in genomic instability. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 173-89. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

AMPLIFICACAO; FUSAO CROMOSSOMICA; ELIMINACAO; DUPLICACAO; INSTABILIDADE GENOMICA; ISOCHROMOSOME; TELOMERO; TRANSLOCACAO

10727/13381US=92 / Biol/Mol
Dupré A, Gautier J. DNA damage response, signalling pathways, and tumorigenesis: overview of the DNA damage checkpoint. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 193-221. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

ATM; ATR; CHECKPOINTS; REPLICA; CADEIA SIMPLES DE DNA; REPARO DE QUEBRA DE DUPLA FITA DO DNA

10728/13381US=92 / Biol/Mol
Maclean KH, Cleveland JL. DNA damage response, signalling pathways, and tumorigenesis: interactions between Myc- and cyclin-dependent kinase inhibitors in cancer. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 223-41. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

MYC; CDK; INIBIDORES DE CDK; INK4; CIP/KIP; CICLINA

10729/13381US=92 / Biol/Mol
Chronis F, Ragakou EP. DNA damage response, signalling pathways, and tumorigenesis: interplay between yH2AX and 53BP1 pathways in DNA double-strand break repair response. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 243-63. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

H2AX; 53BP1; REPARO DE DNA; QUEBRAS DE DUPLA VERTENTE; CROMATINA

10730/13381US=92 / Biol/Mol
Povirk LF. DNA damage response, signalling pathways, and tumorigenesis: DNA-dependent protein kinase in repair, apoptosis, telomere maintenance, and chemotherapy. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 265-78. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

ACABAR JUNTANDO RADIACAO; RUPTURAS DE FILAMENTOS DUPLOS; REPARO DO DNA; KU; ARTEMIS; REPARACAO FOCOS

10731/13381US=92 / Biol/Mol
Dent P, Curiel DT, Fisher PB. Resistance and sensitization: resistance/signaling pathways. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 281-98. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

RADIACAO; SINALIZACAO; QUINASE; FOSFATASE; ESPECIES REATIVAS DE OXIGENIO / NITROGENIO; RECEPTOR

10732/13381US=92 / Biol/Mol
Cabot MC. Resistance and sensitization: ceramide and multidrug resistance. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 299-312. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

CERAMIDA; QUIMIOTERAPIA; MULTIRRESISTENCIA; GLICOSILCERAMIDA SINTETASE

10733/13381US=92 / Biol/Mol
Smith DL, Nolden LK, Mills GB, Lu Y. Resistance and sensitization: chemo-and radiosensitization through inhibition of PI3K/Akt signaling. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 313-34. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

FOSFATIDILINOSITOL 3-QUINASE; AKT; SIGNALTRANSDUCTION; TERAPIA ALVO MOLECULAR; QUIMIOSSENSIBILIZACAO; RADIOSSENSIBILIZACAO

10734/13381US=92 / Biol/Mol
Allen GW, Harari PM. Resistance and sensitization: the advancement of epidermal growth factor receptor inhibitors in cancer therapy. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 335-57. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

RECEPTOR DO FATOR DE CRESCIMENTO EPIDERMICO; RADIACAO; APOPTOSE; INIBIDORES DE MOLECULAS PEQUENAS; ANTICORPOS MONOCLONAIS

10735/13381US=92 / Biol/Mol
Houghton JA. Established cancer therapies: antimetabolites. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 361-82. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

ANTIMETABOLITES; MORTE CELULAR; APOPTOSE; CATASTROFE MITOTICA; NECRESIS; SENESCENCIA

10736/13381US=92 / Biol/Mol
Sordet O, Pommier Y, Solary E. Established cancer therapies: topoisomerase I poisons and apoptotic topoisomerase I-DNA complexes. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 383-406. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

MITOCONDRIAS; TRIOXIDO DE ARSENIO; STAUROSPORINA

10737/13381US=92 / Biol/Mol
Larsen AK, Skladanowski A. Established cancer therapies: perturbations of cellular functions by topoisomerase II inhibitors. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 407-22. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

TOPOISOMERASE II; AGENTES ANTICANCERIGENOS; DOXORRUBICINA; ETOPOSIDE; MORTE CELULAR; PARADA DO CRESCIMENTO; APOPTOSE; NECROSE; CATASTRIOHE MITOTICO; INDUZIDA POR DROGAS PSEUDOSENESCENCE; AUTOFAGIA

10738/13381US=92 / Biol/Mol
Woynarowski JM, Woynarowska BA. Established cancer therapies: the significance of poly-targeting in apoptosis induction by alkylating agents and platinum drugs. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 423-63. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

DNA DO ADULTO; DROGAS ALQUILACAO; DROGAS PLATIUM; ALQUILACAO DE PROTEINAS; TADGETING PROTEINA; REGULACAO REDOX

10739/13381US=92 / Biol/Mol
Klein LE, Horwitz SB. Established cancer therapies: contributions of apoptosis ana senescence to cytotoxicity produced by microtubule-stabilizing agents. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 465-76. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

TAXOL; DISCODERMOLIDE; MICROTUBULOS ACELEROU A SENESCENCIA; AGENTES ESTABILIZADORES MIROTUBULE; APOPTOSE; CATASTROFE MITOTICA

10740/13381US=92 / Biol/Mol
Deininger M. Established cancer therapies: tyrosine kinase inhibitors. In: Gewirtz DA, Holt SE, Grant S. Apoptosis, senescence and cancer. 2 ed. New Jersey: Humana Press, 2007. p. 477-508. (Cancer Drug Discovery and Development) ISBN 978-1-58829-527-9.

TERAPIA-ALVO; BCR-ABL; FLT3; EGFR; TYROSISE INIBITORS QUINASE; IMATINIB; GEFITINIB; ERLOTINIB; CANCER; LEUCEMIA

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