9921/13381US=84-A / Biol/Mol
Pardali E, Liu Z, Scharpfenecker M, Dijke P. Transformig growth factor-B in developing and advanced cancers: TGF-B signaling and vascular morphogenesis. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 507-21. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

TGF-B; HHT; ANGIOGENESE; ENDOGLINA; HHT; TRANSDUCAO DE SINAL

9922/13381US=84-A / Biol/Mol
Korc M. Transformig growth factor-B in developing and advanced cancers: Aberrant growth factor-B signaling in human pancreatic cancer: translational implications. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 523-35. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

SMAD7; TGF-BS; AUTODRINE; ANGIOGENESE; CANCER DE PANCREAS; ALVOS TERAPEUTICOS

9923/13381US=84-A / Biol/Mol
Dennler S, Mawviel A, Verrecchia F. Transformig growth factor-B in developing and advanced cancers: TGF-B and stromal influences over local tumor invasion. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 537-51. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

SMAD; TGF-B; ECM REMODELACAO; MIOFIBROBLASTOS; DESMOPLASIA

9924/13381US=84-A / Biol/Mol
McCartney-Francis NL, Wahl SM. Transformig growth factor-B in developing and advanced cancers: TGF-B at the crossroads between inflammation, suppression and cancer. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 553-70. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

TUMORIGENESE; TREG; SUPRESSAO; TGF-B; LINFOCITOS T; MACROFAGOS

9925/13381US=84-A / Biol/Mol
Datta PK, Mann JR. Development of inhibitors of transforming growth factor-B signaling for therapy: transforming growth factor-B (TGF-B) signaling inhibitors in cancer therapy. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 573-87. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

TGF-B; PEQUENA MOLECULA INIBIDORES; TRANSDUCAO DE SINAL; SUPRESSOR DE TUMOR; PROMOTOR DE TUMOR; BIOMARCADOR; TERAPIA DO CANCER

9926/13381US=84-A / Biol/Mol
Boerma M, Wang J, Corbley MJ, Hauer-Jensen M. Development of inhibitors of transforming growth factor-B signaling for therapy: targeting TGF-B as a strategy to ameliorate intestinal side effects of radiation therapy. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 589-608. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

FATOR TRANSFORMADOR DE CRESCIMENTO-B; COLAGENO; FIBROSE; RADIOTERAPIA; LESOES DE RADIACAO; RECEPTORES DE FACTOR DE CRESCIMENTO TRANSFORMANTE-B; MATRIZ EXTRACELULAR

9927/13381US=84-A / Biol/Mol
Reiss M. Development of inhibitors of transforming growth factor-B signaling for therapy: targetin transforming growth factor-B in metastasis: in vitro and in vivo mechanisms. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 609-34. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

FATOR TRANSFORMADOR DE CRESCIMENTO - B; ANGIOGENESE; CANCER; MOTILIDADE; RESPOSTA IMUNE; INVASAO; METASTASE; TGF-B DO TIPO I; INIBIDOR DA QUINASE DO RECEPTOR; CRESCIMENTO TUMORAL

9928/13381US=84-A / Biol/Mol
Schlingensiepen KH, Jachimczak P, Fischer-Blass B, Fischer D, Specht H, schmaus S, Schlingensiepen R. Development of inhibitors of transforming growth factor-B signaling for therapy: targeted downregulation of TGF-B2 with AP 12009 in tumor therapy. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 635-51. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

OLIGODEOXINUCLEOTIDOS ANTISENSE; CANCER; GLIOMA MALIGNO; TGF-B; USO TERAPEUTICO

9929/13381US=84-A / Biol/Mol
Naumann U, Weller M. Development of inhibitors of transforming growth factor-B signaling for therapy: modulating TGF-B receptor signaling: a novel approach of cancer therapy. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 653-69. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

TGF-B; TGF-B RECEPTORES; MOLECULAS PEQUENAS; DOMINANTE NEGATIVO; RECEPTOR SOLUVEL

9930/13381US=84-A / Biol/Mol
De Crescenzo G, Chao H, Zwaagstra J, Durocher Y, O'Connor-McCourt MD. Development of inhibitors of transforming growth factor-B signaling for therapy: engineering TGB-B traps: artificially dimerized receptor ectodomains as high-affinity blockers of TGF-B action. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 671-84. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

FACTOR DE CRESCIMENTO TRANSFORMANTE-B; ANTAGONISTA; BETAGLICAM; ARMADILHA LIGANTE; RECEPTOR ECTODOMINIO

9931/13381US=84-A / Biol/Mol
Ling LE, Singh J, Chuaqui CE, Boriack-Sjodin PA, Corbley MJ, Lepage DJ, Silverio EL, Sun L, Papadatos JL, Shan F, Pontz T, Kam Cheung H, Zhang X, Arduini RM, Mead JN, Newman MN, Bowes S, Josiah S, Lee WC. Development of inhibitors of transforming growth factor-B signaling for therapy: the use of virtual screening in ALK5 kinase inhibitor discovery and validation of orally active ALK5 kinase inhibitors in oncology. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 685-96. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

VIRTUAL; FARMACOFORO; INIBIDOR DE CINASE; ALK5; TGF-B RECEPTOR TIPO I; CRISTALOGRAFIA DE RAIOS X; TGF-B

9932/13381US=84-A / Biol/Mol
Suzuki E, Albelda SM. Development of inhibitors of transforming growth factor-B signaling for therapy: soluble type II transforming growth factor-B receptor inhibits tumorigenesis by augmenting host ntitumor immunity. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 697-706. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

TGF-B; IMUNIDADE ANTITUMORAL; MESOTELIOMA MALIGNO; SOLUVEL DO TIPO II DO RECEPTOR DE TGF-B

9933/13381US=84-A / Biol/Mol
Lacher MD, Korn WM, Akhurst RJ. Development of inhibitors of transforming growth factor-B signaling for therapy: reversal of EMT by small-molecule inibitors of TGF-B type I and II receptors: implications for carcinoma treatment. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 707-22. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

TGF-B RECEPTORES; PEQUENAS MOLECULAS INIBIDORES; EPITELIAL PARA MESEACHYMAL TRANSICAO; EMT; METASTASE; VIRUS COXSACKIE E RECEPTOR ADENOVIRUS; TERAPIA DO CANCRO ADENOVIRAL

9934/13381US=84-A / Biol/Mol
Bandyópadhyay A, Sun L. Development of inhibitors of transforming growth factor-B signaling for therapy: soluble TGF-B type III receptor suppresses malignant progression of human cancer cells. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 723-35. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

ANGIOGENESE; METALOPROTEINASE DE MATRIZ-9; METASTASE PULMONAR; METASTASE OSSEA; BETAGLICAM SOLUVEL; TGF-B; TGF-B TIPO DE INIBIDORES DO RECEPTOR III; TUMORIGENESE

9935/13381US=84-A / Biol/Mol
Hoffmann FM, Cui Q, Lim SK, Zhao BM. Development of inhibitors of transforming growth factor-B signaling for therapy: targeting smad-dependent TGF-B signaling with peptide aptamers. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 737-56. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

APTAMEROS PEPTIDEO; MOTIVO DE PROTEINA; PROTEINA ANDAIME; SMAD; TGF-B INIBIDORES

9936/13381US=84-A / Biol/Mol
Hsu FJ, Teicher BA, McPherson JM. Development of inhibitors of transforming growth factor-B signaling for therapy: rationale for anti-TGF-B antibody therapy in oncology. In: Jakowlew SB. Transforming growth factor-beta in cancer therapy: cancer treatment and therapy. Amsterdam: Elsevier, 2008. p. 757-74. (Cancer Drug Discovery and Development) ISBN 978-1-58829-715-0.

FACTOR DE CRESCIMENTO TRANSFORMANTE-B; IMUNOSSUPRESSAO; METASTASE OSSEA; CARCINOMA DE CELULAS RENAIS; MELANOMA; CANCER DE MAMA; HORMONAL DO CANCER DA PROSTATA REFRATARIOS; CANCER DE PANCREAS; MIELOMA MULTIPLO; LINFOMA DE NAO-HOGGKIN; BIOMARCADORES

9937/13381US=86 / Biol/Mol
Zakeri Z, Lockshin RA. Cell dealth: history and future. In: Khosravi-Far R, White E. Programmed cell death in cancer progression and therapy. New York: Springer, 2008. p. 1-11. (Advances in Experimental Medicina and Biology, 615) ISBN 978-1-4020-6553-8.

MORTE CELULAR; APOPTOSE; AUTOFAGIA; MORTE CELULAR AUTOFAGICA; HISTORICO; LISOSSOMA

9938/13381US=86 / Biol/Mol
Salvesen GS, Riedl SJ. Caspase mechanisms. In: Khosravi-Far R, White E. Programmed cell death in cancer progression and therapy. New York: Springer, 2008. p. 13-23. (Advances in Experimental Medicina and Biology, 615) ISBN 978-1-4020-6553-8.

CASPASE; MECANISMOS DE CASPASE; APOPTOSSOMO; DISC; IAP; INIBICAO; PROTEASE; ZIMOGENIO; APOPTOSE

9939/13381US=86 / Biol/Mol
Chalah A, Khosravi-Far R. The mitochondrial death pathway. In: Khosravi-Far R, White E. Programmed cell death in cancer progression and therapy. New York: Springer, 2008. p. 25-45. (Advances in Experimental Medicina and Biology, 615) ISBN 978-1-4020-6553-8.

VIA DE MORTE MITOCONDRIAL; APOPTOSE; RECEPTORES DE MORTE; MITOCONDRIAS; MEMBRANAS; FOSFOLIPASES; CARDIOLIPINA; LIBERACAO DE FATORES PRO-APOPTOTICOS; CITOCROMO C; FATOR DE INDUCAO DE APOPTOSE; SMAC / DIABLO; HTRA2/OMI; ENDONUCLEASE G; PROTEINAS MITOCONDRIAIS; ATIVACAO DA CASPASE; FAMILIA BCL-2; STRESS OXIDATIVO; CANCER

9940/13381US=86 / Biol/Mol
Melet A, Song K, Bucur O, Jagani Z, Grassian AR, Khosravi-Far R. Apoptotic pathways in tumor progression and therapy. In: Khosravi-Far R, White E. Programmed cell death in cancer progression and therapy. New York: Springer, 2008. p. 47-79. (Advances in Experimental Medicina and Biology, 615) ISBN 978-1-4020-6553-8.

VIAS APOPTOTICAS; PROGRESSAO TUMORAL; TERAPIA DE CANCER; APOPTOSE; INIBIDORES; TRANSDUCAO DE SINAL; ONCOGENE; MAQUINARIA APOPTOTICA; DROGAS QUIMIOTERAPICAS; RESISTENCIA A DROGA

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